Diagnostic Neuropathology Smears

This textbook provides practical information on how to perform and interpret smears and use smears for diagnostic intraoperative neuropathology. The book covers most aspects of brain biopsies that require intraoperative or "frozen section" diagnosis, including tumors, non-neoplastic lesions, infectious diseases, and metastases to the brain. The author also discusses more general aspects of smears, including their preparation and general interpretation. Emphasis is on the structural information about brain lesions supplied by the technique of smears, as well as the patterns of smears produced by different tumors. More than 200 full-color illustrations complement the text.
Diagnostic Neuropathology Smears by Joseph is an excellent resource for the general pathologist. As the book explains, smears are superior to frozen sections for the intraoperative assessment of brain lesions in the vast majority of cases (they conserve tissue, minimize artifacts, and provide additional information to the permanent sections). However, no general pathology or cytology text that I am aware of adequately addresses the CNS.
The photomicrographs in this book are superb, including low, medium, and high power views of all the major diagnostic entities (neoplastic and reactive), as well as gross photos and MRIs, which need to be correlated to the slides for maximum accuracy. Differentials and pitfalls are discussed and there is also an introduction to the approach to smears for the non cytologist. If you're studying for AP/CP boards, you should probably study something else, but if you are going to be alone in the frozen section room with one of these CNS lesions, this is the book to learn. I'm a cytology fellow about to go into general practice, and I'm glad I read this book.
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